Sodium nitroprusside-induced hypotension and renal blood flow

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Cerebral blood flow and metabolism during hypotension induced with sodium nitroprusside.

Cerebral blood flow and metabolism have been studied in 11 patients during general anaesthesia and hypotension induced with sodium nitroprusside in combination with captopril. Cerebral blood flow was measured, using a Novo Cerebrograph model 10A, after injection of 133 xenon into an arm vein. Arterial and venous blood samples were drawn to calculate cerebral metabolism. Captopril 1 mg.kg-1 oral...

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Effect of sodium nitroprusside-induced hypotension on pulmonary deadspace.

Deliberate hypotension with nitroprusside produced a 40% reduction in mean arterial pressure, but it did not cause any change in the pulmonary deadspace to tidal volume ratio ( Vb/ Vr). This was achieved by adequate hydration both before and during hypotension, as indicated by constant filling pressures. Thus we have shown that deliberate hypotension per se does not increase Vb/ VT, and that va...

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Effect of hypotension induced with sodium nitroprusside on canine coronary arterial flow.

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Deliberately Lowering Blood Pressure with Sodium Nitroprusside

The goal of hyptensive anesthesia is the safe reduction of intraoperative blood loss, thus reducing transfusion risks.  Previous hypotensive technics had a narrow margin of safety in that cardiac output was usually reduced in proportion to the degree of induced hypotension. This is in contrast to the results of our study, in which Sodium Nitroprusside was used as the sole hypotensive agent. Ni...

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ژورنال

عنوان ژورنال: Canadian Anaesthetists’ Society Journal

سال: 1977

ISSN: 0008-2856,1496-8975

DOI: 10.1007/bf03006707